Daktari CD4

Medical equipment data
Health topic HIV/AIDS
Health classification Diagnosis
Project data
Type
Authors
Location Massachusetts, United States
Status Clinical trial
Years
Made No
Replicated No

Problem being addressed

There is a need to develop CD4 counters that do not rely on laboratory workers and expensive/complicated equipment. A counter that can be used by rural clinicians in the field without extensive training would greatly assist in managing HIV in rural areas.

Detailed description of the solution

Microfluidic cell chromatography isolates cells and other particles in a miniature sensing chamber, without the complex manual steps of blood tests. The system takes advantage of electrochemical sensing, using lysate impedance spectroscopy. The system uses a simple sensor that counts the captured CD4 cells by measuring their internal contents electrically. A hand-held instrument interprets the electrical signal, and reports the CD4 count within minutes.

Designed by

  • Designed by: Daktari Diagnostics
  • Manufacturer location: Cambridge, Massachusetts, USA

When and where it was tested/implemented

A clinical trial took place in Seattle the summer of 2010 and clinical trials have also been conducted in Uganda.

Funding Source

Funded privately and through the Gates Foundation.

References

Externally generated reports

McBride R. (2009.) Daktari Diagnostics, backed by Gates Foundation, raises funds for HIV test study. Link available here

Page data
Authors Evashiu
License CC-BY-SA-3.0
Cite as Evashiu (2012–2022). "Daktari CD4". Appropedia. Retrieved November 28, 2025.